Contact Members/Sign Up Reg Form

US Launches Trial of New Nasal Covid-19 Vaccine Promising Alternative to Injection

A Phase 1 clinical trial has commenced to assess an experimental nasal vaccine designed to protect against emerging variants of SARS-CoV-2, the virus responsible for Covid-19. Led by scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), this trial aims to evaluate the safety and efficacy of the new vaccine delivery method.

Dr. Jeanne M. Marrazzo, Director of NIAID, emphasized the critical need for next-generation vaccines amidst the evolving landscape of Covid-19 variants. She highlighted that while current vaccines have been effective in preventing severe illness and death, they have shown limitations in stopping infections and mild cases. The development of nasal vaccines, she added, could potentially reduce infections and transmission rates, particularly with the emergence of new virus variants.

The trial is currently enrolling 60 healthy adults aged 18 to 64 at three locations across the United States: Baylor College of Medicine in Houston, The Hope Clinic of Emory University in Decatur, Georgia, and New York University on Long Island. Participants must have previously received at least three doses of an FDA-approved mRNA Covid-19 vaccine.

Led by Dr. Hana M. El Sahly at Baylor College of Medicine, the trial participants will be divided into three groups, each receiving varying doses of the experimental nasal spray vaccine. Over the course of a year, researchers will closely monitor the vaccine's safety profile and its ability to elicit immune responses both in the bloodstream and within nasal tissues.

Details of the Nasal Vaccine

The investigational vaccine, known as MPV/S-2P, employs murine pneumonia virus (MPV) as a vector to deliver a stabilized version of the SARS-CoV-2 spike protein. MPV does not cause disease in humans but targets respiratory cells, potentially enhancing the delivery of the vaccine to the respiratory tract.

Prior pre-clinical studies conducted in non-human primates demonstrated that MPV/S-2P was safe and well-tolerated, inducing robust immune responses in both systemic circulation and mucosal tissues of the respiratory tract. This suggests that the vaccine could stimulate effective mucosal immunity in the nose and throat, which is crucial for combating respiratory viruses.

The initiation of this Phase 1 trial marks an important step in advancing the development of nasal Covid-19 vaccines, aiming to bolster the arsenal against the ongoing pandemic by potentially enhancing vaccine efficacy and broadening protection against emerging variants of SARS-CoV-2.

July 4, 2024 11:04 a.m. 417

#trending #latest #NasalVaccine #COVID19Research #Phase1Trial #NIHResearch #SARS-CoV-2 #VaccineDevelopment #EmergingVariants #MucosalImmunity #ClinicalTrial #HealthScience #breakingnews #worldnews #headlines #topstories #globalUpdate #dxbnewsnetwork #dxbnews #dxbdnn #dxbnewsnetworkdnn #bestnewschanneldubai #bestnewschannelUAE #bestnewschannelabudhabi #bestnewschannelajman #bestnewschannelofdubai #popularnewschanneldubai

Explore Cultural Tourism: Discover Heritage and Traditions Worldwide

travel & tourism / tourism trends
July 24, 2024 4 a.m. 362

Discover the magic of cultural tourism by exploring heritage and traditions around the globe. Immerse yourself in local customs, vibrant festivals, and historic...Read More.

Top Adventure Spots: Fun Activities for Every Thrill-Seeker

travel & tourism / tourism trends
July 24, 2024 3 a.m. 381

Explore the world of adventure tourism with top destinations and thrilling activities for thrill-seekers. Discover mountain climbing in the Himalayas, scuba div...Read More.

Explore Cultural Tourism: Discover Heritage and Traditions Worldwide

Discover the magic of cultural tourism by exploring heritage and traditions around the globe. Immerse yourself in local customs, vibrant festivals, and historic

Top Adventure Spots: Fun Activities for Every Thrill-Seeker

Explore the world of adventure tourism with top destinations and thrilling activities for thrill-seekers. Discover mountain climbing in the Himalayas, scuba div

Easy Tips for Healthy Aging: Stay Active and Well as You Grow Older

Discover essential tips for healthy aging with our guide. Learn how to stay active, eat a balanced diet, prioritize mental health, maintain social connections,

How Yoga Helps You Get Stronger and More Flexible for Better Fitness

Explore the many benefits of yoga for physical fitness! Discover how yoga boosts flexibility, builds strength, improves balance, enhances posture, and reduces s

Afghanistan Seeks Tri-Series Matches Against Pakistan and UAE

The Afghanistan Cricket Board proposes a tri-series with Pakistan and UAE, plus A team tours to Bangladesh and Zimbabwe.

Drone Alert Issued by Dubai Police: Residents Urged to Follow Guidelines

Authority explains drone presence in your area and how to identify them.

New SR3,000 Fine for Illegal Fire Setting in Restricted Areas

Special Forces for Environmental Security warn of fines for setting fires outside designated areas.

The Most Intense Sports Rivalries: Top Matches and Exciting Showdowns

Explore the world of intense sports rivalries! From soccer showdowns to basketball battles, discover what makes these matchups thrilling and unforgettable. Dive

Ethiopia Landslide Claims 55 Lives, Authorities Confirm Fatalities

A landslide triggered by heavy rains hit a mountainous area in South Ethiopia's regional state, according to authorities.

Economic Partnership Pact Signed by UAE's bin Rashid, Mauritius PM

Sheikh Mohammed bin Rashid and Mauritius PM Pravind Kumar Jugnauth witnessed the signing of a landmark Comprehensive Economic Partnership Agreement (CEPA).

Sri Lanka Unveils T20I Squad vs India, New Captain Appointed

The 27-year-old Asalanka, with significant captaincy experience, led Sri Lanka in two T20Is in Bangladesh earlier this year while Hasranga was suspended.

Priyanka Chopra Masters Gen-Z Fashion with Satin Tracksuit and Sneakers for Whale Watching

Priyanka Chopra Jonas shared photos on Instagram from a family whale-watching trip, showcasing a stylish and comfy look that we can’t get enough of.

Philippines Imposes Ban on Chinese-Operated Online Gambling Sites

Philippines President bans Chinese-run online gambling outfits, which employ thousands of Chinese and Southeast Asians, amid a Beijing-backed crackdown.

Gaza’s Khan Younis Sees 70 Deaths as Israel Sends Tanks Back After Evacuation

Gaza medics reported that Palestinians were killed by tank fire and aerial bombardments in Bani Suhaila and other eastern towns of Khan Younis.

Gustavo Petro Signs Landmark Bill to Ban Bullfighting in Colombia

Colombian President Gustavo Petro signs a bill banning bullfights, with the ban set to take effect by 2027.

Dubai Completes Installation of Over 1 Million Smart Water Meters

HE Saeed Mohammed Al Tayer announced DEWA has completed 100% installation of over one million smart water meters in Dubai, meeting high international standards.

Top 5 Brightest Natural Wonders Around the World: See the Great Barrier Reef and More

Explore the world's most colorful natural wonders with our guide! From the vibrant Great Barrier Reef in Australia to the stunning Rainbow Mountains in China, d

Govt to Formally Accept SC Decision on Job Quotas, Says PM Hasina

DHAKA: PM Sheikh Hasina’s government will accept the SC ruling abolishing most government job quotas, following recent deadly nationwide protests.

WhatsApp Enhances Status Updates with New Fix Feature

WhatsApp is set to improve status updates with a new feature designed to enhance the visual quality of images and videos.

Prince George Turns 11: David Beckham Shares Warm Birthday Wishes

Former football star David Beckham has sent heartfelt birthday wishes to Prince George, the eldest son of Prince William and Kate Middleton.

Get In Touch

3001E, 30 Floor, Aspin Commercial Tower, Sheikh Zayed Road, Dubai, UAE

+971 56 450 3476

Follow Us

© DNN. All Rights Reserved.